SAMe 200 mg 60 vcaps

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SAMe 200 mg 60 vcaps

SAMe (S-adenosylmethionine), a compound native to the body, is a critical component of many biochemical reactions, including those that affect brain biochemistry and joint health. Numerous studies have indicated that SAMe can help to temporarily alleviate aches and pains resulting from overexertion or stress. In addition, because SAMe is also necessary for the synthesis of neurotransmitters, it plays an important role in the maintenance of a positive mood. Protocol® SAMe is enteric coated, which makes it very well tolerated and protects it from degradation. *

  • Nervous System Support
  • Supports Joint Health*
  • Contains no sugar, salt, starch, yeast, wheat, gluten, soy, milk, egg, shellfish, or preservatives

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested Use

Take 1 capsule 2 to 4 times daily, or as directed by your healthcare practitioner.

Refrigeration recommended after opening.

Cautions and Interactions:

  • Individuals with bipolar (manic) depression should not take SAMe unless under professional medical supervision.
  • There have been reports of SAMe interacting with anti-depressant medications and increasing the potential for side effects including headache, irregular or accelerated heart rate, anxiety, and restlessness.
  • SAMe may affect the body's reactions to Levodopa used for Parkinson's disease. However, it might also reduce its effectiveness over time.
  • People taking SAMe should supplement its use with a multivitamin that contains folic acid and vitamins B12 and B6.*


Serving Size: 1 capsule
Servings Per Container: 60

Ingredients Amount %DV*
SAMe (S-Adenosyl-L-Methionine)
  (from S-Adenosyl-L-Methionine Disulfate Tosylate)
200 mg
Other Ingredients: Hypromellose (cellulose capsule), Microcrystalline cellulose, silicon dioxide, and stearic acid (vegetable source).

* % Daily Values are based on a 2,000 calorie diet.
† Daily Value not established