Description Usage Supplement Facts Nicotinamide Riboside with Resveratrol and Cofactors all in one capsule! Supports healthy aging* Helps regulate metabolism for improved metabolic syndrome parameters* Nicotinamide riboside (NR) – the most efficient direct precursor to NAD+* Resveratrol and quercetin increase the activity of sirtuins* Betaine provides important methylation factors* Nicotinamide Riboside (NR) The most direct precursor to NAD+ – it's essential for mitochondria to perform their myriad functions* Important in the regulation of cellular aging* Provides support for metabolic syndrome* NR is the most direct precursor to nicotinamide adenine dinucleotide (NAD+).* The mitochondria cannot perform their crucial cellular functions without a sufficient supply of NAD+.* NR offers fundamental support for mitochondrial biogenesis, as well as all other mitochondrial activities – from energy production to the regulation of metabolism and cellular aging.* Resveratrol Purely trans-resveratrol – not a diluted plant extract Increases activity of the sirtuins – SIRT1 and SIRT3, in particular* Provides benefit for metabolism and for healthy aging* Resveratrol mimics the effect of calorie restriction by activating the sirtuin group of proteins.* In one study, resveratrol was shown to be the most potent natural activator of the sirtuins.* Resveratrol shows promise in helping attenuate the effects of several age-related conditions.* Quercetin Phytosome Quercetin is bound to sunflower-sourced phospholipids for enhanced absorption* Enhances sirtuin activity* Slows the breakdown of resveratrol in the body* Research shows that quercetin not only acts as a potent antioxidant and is synergistic with the activities of resveratrol, it also slows the breakdown of resveratrol in the body.* Like resveratrol, quercetin also enhances sirtuin activity.* Betaine Important methyl donor* Provides nutrient support for fatty liver* Supports homocysteine metabolism* Betaine – also known as trimethylglycine – is a premier methyl donor.* In addition to providing significant methylation support because it can donate three methyl groups, betaine provides support for important metabolic functions that are associated with metabolic syndrome.* *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Suggested Use Take 2 capsules one to two times daily or as recommended by your health-care practitioner. ALLERGY WARNING This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. PREGNANCY If pregnant, consult your health-care practitioner before using this product. INTERACTIONS There are no known adverse interactions or contraindications at publication date. SUPPLEMENT FACTS Serving size: 2 capsules Servings per container: 30 Ingredients Amount %DV Nicotinamide Riboside Chloride†† 300 mg † Quercetin Phytosome (Sophora japonica concentrate (leaf)/Phospholipid complex from Sunflower) 250 mg † Trans-Resveratrol 150 mg † Betaine Anhydrous (Trimethyglycine) 50 mg † * % Daily Values are based on a 2,000 calorie diet.† Daily Value not established. Other Ingredients: High and low viscosity hydroxypropyl methylcellulose, Leucine, MagnesiumCitrateLaurate (Time-Sorb†††), Hypromellose (derived from cellulose) capsule, Silicon Dioxide. ††This product contains ChromaDex Inc.’s proprietary Nicotinamide Riboside ingredient, Niagen®. Niagen is a registered trademark of ChromaDex, Inc. †††The ingredients in this product are complexed with Time-Sorb®, a time-release matrix.