Description Usage Supplement Facts PureGenomics B-Complex is designed to address the nutrient requirements of common genetic variations in the methylation pathway with a unique blend of B vitamins in highly researched and activated forms. Methylation is a key regulator of genetic expression and cellular function. Healthy methylation is vital for cellular health, DNA synthesis, hormone and neurotransmitter production, and energy metabolism. Optimal levels of B vitamins have been associated with cellular, cardiovascular, neurological and psychological health. B vitamins are essential to basal mitochondrial function as metabolic coenzymes, playing a key role in energy production and nutrient metabolism. Folate is offered in this formula as Metafolin 5-methyltetrahydrofolate (5-MTHF), the universally metabolized and biologically active form of folate, providing support for individuals with genetic variations in the MTHFR gene. Vitamin B12 is offered as a combination of hydroxycobalamin and adenosylcobalamin. Hydroxycobalamin is a precursor form of vitamin B12 converted in the body to both methylcobalamin and adenosylcobalamin. Adenosylcobalamin is an activated form stored in the mitochondria of cellular tissues. It is a key cofactor in carbohydrate metabolism and healthy synthesis of neuronal myelin. Benfotiamine is a lipid-soluble, enhanced-retention thiamin derivative targeting glucose metabolism to support vascular and neuronal health.* *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Suggested Use Adults: As a dietary supplement, take 1 capsule daily, with a meal, or as directed by a health professional. If you are pregnant, nursing, or undergoing treatment for a medical condition, please consult your healthcare professional before using this product. Store in a cool, dry place and tightly capped. Keep out of the reach of children. Tamper resistant package, do not use if outer seal is missing. SUPPLEMENT FACTS Serving size: 1 capsuleServings per container: 120 Ingredients Amount %DV Thiamin (as thiamin HCl) (B1) 25 mg 2,083% Riboflavin (As Vitamin B2 and 67% Riboflavin 5' Phosphate (Activated B2)) 15 mg 1,154% Niacin (As Niacinamide) 50 mg 313% Vitamin B6 (As Pyridoxine HCI and 20% Pyridoxal 5' Phosphate (Activated B6)) 50 mg 2,941% Folate (As Metafolin® L-5-MTHF 800mcg) 1,333 mcg (DFE) 333% Vitamin B12 (As Adenosylcobalamin and 50% hydroxycobalamin) 800 mcg 33,333% Biotin 400 mcg 1,333% Pantothenic Acid (As Calcium Pantothenate) (B5) 100 mg 2,000% Choline (As Choline Bitartrate) 40 mg 7% Inositol 25 mg † BenfoPure® Benfotiamine 3 mg † * % Daily Values are based on a 2,000 calorie diet.† Daily Value not established. Other Ingredients: vegetarian capsule (cellulose, water), ascorbyl palmitate. Contains no: gluten, artificial additives, allergens, GMOs, environmental contaminants or added excipients. Hypoallergenic.