Description Usage Supplement Facts Helps to modulate the Th2 immune response and maintain Th1/Th2 balance at the cellular level* The PureResponse™ formula Th2 Modulator is designed to support healthy Th1/Th2 balance and mucosal health. Modulating Th2 status helps to maintain Th1/Th2 balance and offers support for self-tissue response. Th2 response is affected by stress, aging, and cytokine changes resulting from metabolic, hormonal, physiological, and environmental factors. The product helps support healthy modulation of Th2 cytokines, and eosinophil and mast cell activity. It also helps maintain healthy modulation of mucosal immune responses to environmental factors. Th2 modulation may be indicated when addressing immune balance in the sinus, respiratory, urinary, and intestinal tracts. Perilla maintains healthy upper respiratory cytokine levels in animal models of Th2 dominance. It also supports cytokine homeostasis of GI mucosal tissue. In a randomized controlled trial involving 50 individuals, 150 mg of Perilla frutescens extract twice daily offered statistically significant support for GI comfort. N-acetyl-l-cysteine (NAC) offers mucolytic properties and promotes tissue levels of glutathione – a key component of the antioxidant defense system – to support the body's natural defense system. Lymphocytes rely on glutathione to function properly. It is believed to be through this antioxidant mechanism that NAC supports healthy Th1/Th2 balance and cytokine production to maintain tissue health. A multicenter, randomized, double-blind trial with 262 participants indicated that NAC supplementation for six months supported upper respiratory tract and immune system health. Quercetin is known for its antioxidant activity and immune support properties, including support for Th1/Th2 balance and cytokine balance. Astragalus may help modulate the relationship between Th1 and Th2 cytokines.* Part of the PureResponse™ Immune Protocol* for healthy immune balance and function* Immune Supporting Blend: Contains a blend of N-acetyl-l-cysteine (NAC), quercetin, perilla seed and astragalus extracts Antioxidant Support: N-acetyl-l-cysteine (NAC) offers mucolytic properties and promotes tissue levels of glutathione – a key component of the antioxidant defense system.* Offers support for self-tissue response* Promotes sinus, respiratory and gastrointestinal function* Free From: Pure Encapsulations products are free from wheat, gluten, egg, peanuts, magnesium stearate, hydrogenated fat, artificial sweeteners and colors, and other unnecessary excipients. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Suggested Use Adults: As a dietary supplement, take 2 capsules, 1-2 times daily, between meals, or as directed by a healthcare professional. If you are pregnant, nursing, or undergoing treatment for a medical condition, please consult your healthcare professional before using this product. Store in a cool, dry place and tightly capped. Keep out of the reach of children. Tamper resistant package, do not use if outer seal is missing. SUPPLEMENT FACTS Serving size: 2 capsulesServings per container: 60 Ingredients Amount %DV* N-Acetyl-L-Cysteine 300 mg † Quercetin 250 mg † Perilla (Perilla frutescens) extract (seed) (standardized to contain 3% polyphenols) 150 mg † Astragalus (Astragalus membranaceous) extract (root) 160 mg † Other Ingredients: vegetarian capsule (cellulose, water), hypoallergenic plant fiber (cellulose) * % Daily Values are based on a 2,000 calorie diet.† Daily Value not established. Contains no: GMOs, gluten. Hypoallergenic.