Description Usage Supplement Facts Natural progesterone, now referred to as bio-identical progesterone, is structurally the same as human progesterone and releases the full range of biologic activity of hormone produced naturally by the body. Transdermal progesterone passes through the skin into capillaries in the underlying fat layer and is passively diffused into the blood stream. In contrast to oral progesterone which is subject to removal by the liver, transdermally-applied progesterone escapes this first-pass effect to retain potency when modest amounts are used. Progesterone deficiencies may occur in association with disturbances in premenstrual and menopausal health. Progesterone facilitates bone deposition while balancing the effects of estrogen. Natural progesterone is just as effective as, and much safer than, synthetic progesterone. Supportive factors in Progesterone Plus include primrose oil and extracts of chasteberry, wild yam, and black cohosh.* *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Suggested Use Adults: Progesterone, being a small, fat-soluble molecule, is easily absorbed through the skin. For general application, skin sites recommended include the inner areas of the thighs and arms, neck, upper chest and abdomen. The site should be rotated daily for maximum absorption. Allow 2-3 months for maximum effect. For external use only. Consult your doctor if you have a medical condition, if you are or may become pregnant, or are nursing. Store at room temperature. Keep out of the reach of children. Tamper resistant package, do not use if seal is missing. SUPPLEMENT FACTS Serving size: 1 gram (¼ tsp)Servings per container: Approx. 56 Ingredients %DV Purified water, Organic Jojoba Oil, Organic Aloe Leaf extract, Organic Shea Butter, Cetyl Alcohol (coconut oil derived), Stearic acid (palm kernel derived thickener), USP Progesterone derived from Wild Yam (Dioscorea villosa) Root extract, Evening Primrose Oil, Sodium Hydroxymethylglycinate, Disodium Edetate, Potassium Sorbate, Xanthan Gum, Tocopheryl Acetate (Vitamin E), Organic Black Cohosh extract, Chasteberry extract † Other Ingredients: none † Daily Value not established. 25 mg of progesterone per serving.