Description Usage Supplement Facts Supports the immune system and gastrointestinal (GI) system health* Includes the probiotic strains in Kirkman’s popular Pro-Bio Gold™ plus Saccharomyces boulardii. Free of common allergens. Gluten and casein free. 90 vegetarian capsules. Purity Tested®. Pro-Bio Defense™ contains the most important “resident” and “transient” microorganisms that contribute to maintaining and promoting a healthy GI tract.* It offers the six probiotic strains in Kirkman’s popular Pro-Bio Gold™ with added Saccharomyces boulardii (S. boulardii), a special strain of yeast that has probiotic capabilities.* S. boulardii is considered a non-colonizing baker’s yeast species, which is very closely related to brewer’s yeast also known as S. cervesiae. Although it is a “yeast,” it is not related to the Candida species (Candida albicans, tropicalas, etc.), which can cause unhealthy microorganisms in the GI system and genitourinary tracts. It is known to be effective to support digestion when used alone or in combination with other probiotics.* All six probiotic strains used in Pro-Bio Defense™ have undergone DNA finger printing to support their identities and have exhibited long-term stability. More than 65 scientific studies and published articles have been written in support of the strains, documenting the ability of these strains to: possess a high tolerance to survive stomach acids and bile salts support the body’s natural defenses and the intestinal tract’s immune system* help alleviate occasional diarrhea and constipation* address lactose metabolism issues* adhere to and colonize the GI mucosal membrane* assist with regulating intestinal mobility and normal bowel function* possibly help create an inhibitory effect on free radical activity in the colon* HEAT SENSITIVE ITEM: This product is refrigerated in our warehouse to ensure quality and ships with a FREE cold pack. It is normal for an ice pack to melt before the package arrives at it’s destination, and to be warm to the touch, but the product will not be damaged or degraded during shipping. The ice pack helps maintain a cooler temperature during transit. This product may not ship on a Thursday or Friday (depending on your location) to avoid weekend shipping delays. It WILL NOT be shipped to PO boxes. Orders placed on Thursday may be shipped overnight for Friday delivery at an additional cost. We recommend refrigerating upon delivery. Please note: This product IS NOT RETURNABLE. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Suggested Use One to two capsules daily or as directed by a physician. Keep bottle refrigerated and tightly capped. Do not remove the desiccant bag or oxygen absorber if present. Keep out of reach of children. Heat Sensitive:Overnight shipping is recommended. SUPPLEMENT FACTS Serving size: 1 capsuleServings per container: 100 Ingredients Amount %DV* Kirkman Proprietary Blend Total Probiotic Potency 20 Billion CFUs Saccharomyces Boulardii Lactobacillus Acidophilus Lactobacillus Rhamnosus Bifidobacterium Bifidum/Lactis Lactobacillus Plantarum Lactobacillus Casei Steptococcus Thermophilus 20.1 mg20 billion CFUs † Other Ingredients: Microcrystalline cellulose, vegetarian capsule (hypromellose and water), inulin, silicon dioxide, magnesium stearate (plant based) * % Daily Values are based on a 2,000 calorie diet.† Daily Value not established. Ingredients: Microcrystalline Cellulose, Pyridoxal 5-Phosphate, Silicon Dioxide, Plant Cellulose Capsule. Contains no: Sugar, starch, soy, wheat, casein, gluten, milk, egg, preservatives, gelatin, flavorings, colorings, peanuts, tree nuts or fish.