Description Usage Supplement Facts HMRlignan contains the lignan 7-hydroxymatairesinol, a precursor to enterolactone, which has been associated with a healthy estrogen-to-progesterone ratio and cellular health. As a result, lignans have demonstrated supportive roles in moderating hot flashes as well as promoting breast, uterine, cervical, bone and cognitive health. Importantly, dietary intake of lignans and healthy serum enterolactone levels are also positively associated with healthy cardiovascular function. Lifenol hops extract contains 8-prenylnaringenin (8-PN), supportive for menopausal comfort, antioxidant defense and bone health. Two randomized, double-blind, placebo-controlled studies indicated that Lifenol hops extracts provided support for general menopausal discomfort, night sweats and hot flashes. Questionnaire results scored at six to eight weeks after supplementation suggest that hot flashes were reduced by three to four times compared to placebo. Ashwagandha, rhodiola and maca extracts are powerful adaptogens offering support for positive mood and relaxation. Two randomized controlled trials indicated that ashwagandha offers support for occasional stress and promotes healthy sleep, cognitive function and relaxation. In addition to promoting emotional well-being, maca also offers support for sexual function. While rhodiola has long been known to support endurance, recent research suggests that it may act as a selective estrogen receptor modulator to support cognitive, cardiovascular and bone health related to menopause. Grape seed extract and resveratrol support menopausal comfort, as well as bone, cognitive and cardiovascular health. In a randomized controlled trial, resveratrol supplementation decreased menopausal symptoms from moderate/severe to mild in 78.6% of patients. Numerous studies suggest grape seed polyphenols promote healthy blood vessel relaxation and antioxidant defenses to promote cardiovascular health.* *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Suggested Use Adults: As a dietary supplement, take 1 capsule, twice daily, with meals. If you are pregnant, nursing, or undergoing treatment for a medical condition, please consult your healthcare professional before using this product. Store in a cool, dry place and tightly capped. Keep out of the reach of children. Tamper resistant package, do not use if outer seal is missing. SUPPLEMENT FACTS Serving size: 1 capsuleServings per container: 60 Ingredients Amount %DV HMRlignan (containing 7-hydroxymatairesinol) (from Norway spruce knot wood) 36 mg † Lifenol hop (Humulus lupulus L.) extract (female cone) (standardized to contain 0.15% 8-prenylnaringenin) 42.5 mg † Ashwagandha (Withania somnifera) extract (root) (standardized to contain 2.5% withanolides) 125 mg † Maca (Lepidium meyenii) extract (tuber) 250 mg † Rhodiola (Rhodiola rosea) extract (root) Rhodiola (Rhodiola rosea) extract (root) 50 mg † Rhodiola (Rhodiola rosea) extract (root) (standardized to contain 92% polyphenols) 50 mg † resVida resveratrol (as trans-resveratrol) 12.5 mg † * % Daily Values are based on a 2,000 calorie diet.† Daily Value not established. Other Ingredients: vegetarian capsule (cellulose, water), hypoallergenic plant fiber (cellulose).