Description Usage Supplement Facts Joint stiffness and discomfort is also a consequence of aging. With advancing age, there’s an increase in certain cytokines (immune-modulating agents) that contribute to bone health conditions. Tumor necrosis factor (TNF-alpha) is one such agent. These pro-inflammatory agents have been implicated in a host of age-related problems including issues related to joints. Life Extension's Arthro-Immune Joint Support combines two clinically validated plant extracts into one powerful formula to help ease inflammation. Andrographis paniculata has received acclaim for its beneficial effect on inflammation. A Chilean study involved 60 adults who took either 150 mg andrographis extract daily or a placebo. Those taking the extract showed dramatic improvement of several outcomes, including fewer numbers of tender and/or swollen joints. For joints that remained tender and/or swollen, the intensity was lessened. Arthro-Immune Joint Support contains PARACTIN® Andrographis extract, which has demonstrated its efficacy in easing inflammation in human clinical, in vivo and in vitro studies. Curcumin is a compound that is universally recognized for its impressive antioxidant and fluid-regulating properties. In an as-yet-unpublished double-blind clinical trial, an enhanced absorbing curcumin was shown to have a beneficial effect on inflammation. Arthro-Immune Joint Support also contains BCM-95® Bio-Curcumin®, which is considered the gold standard curcumin, with bioavailability far superior to that of most curcumin extracts. Life Extension’s Arthro-Immune Joint Support provides scientifically validated botanical extracts that have been shown to have significant salutary effects on joint health. Just one capsule a day provides a potent serving of PARACTIN® and BCM-95® Bio-Curcumin®. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Suggested Use Adults: Take one (1) capsule once or twice daily (6 to 8 hours apart) with food, or as recommended by a healthcare practitioner. Do not take if you have gallbladder problems or gallstones. If you are taking anti-coagulant or anti-platelet medications, or have a bleeding disorder, consult your healthcare provider before taking this product. Do not exceed recommended dose. If you are pregnant or nursing, please consult your healthcare professional before using this product. Store in a cool, dry place and tightly capped. Keep out of the reach of children. Tamper resistant package, do not use if outer seal is missing. SUPPLEMENT FACTS Serving size: 1 vegetarian capsule Servings per container: 60 Ingredients Amount %DV PARACTIN (Bioactive 14-Neo-Andro Compounds) patented blend of (Andrographis paniculata) extract (leaf) supplying [Andrographolides, 14-Deoxyandrographolides, and Neoandrographolides] 150 mg † BCM-95 Bio-Curcumin 25:1 extract (root) [std. to 95% Total Curcuminoids Complex with Essential Oils of Turmeric Rhizome by HPLC (237.5mg)] 250 mg † * % Daily Values are based on a 2,000 calorie diet.† Daily Value not established. Other Ingredients: vegetable cellulose (capsule), rice flour, L-leucine, silica. Bio-Curcumin and BCM-95 are registered trademarks of Dolcas-Biotech, LLC. U.S. Patents Nos. 7,883,728, 7,736,679 and 7,879,373. PARACTIN is a registered trademark of HP Ingredients.