Description Usage Supplement Facts PERQUE Activated B-12 Guard is in lozenge form for maximum uptake and optimal delivery to the brain. Studies on PERQUE Activated B-12 Guard lozenge formulation show nearly the same B-12 uptake as from injection. Patients notice that they feel better more quickly.* Vitamin B-12 in our food supply is estimated to be 78% less than in the 1960s. Diet alone is hard pressed to provide the necessary levels of this important nutrient. In addition, stress and reduced hydrochloric acid (HCl) and intrinsic factor production in the stomach impair absorption. The most commonly used forms of B-12 require activation in the body, making uptake quite low – rarely more than 50%.* PERQUE delivers vitamin B-12 in its superior, activated hydroxocobalamin form. Although it is more expensive and difficult to obtain, hydroxocobalamin lasts longer and raises B-12 blood concentrations higher than other forms. For this reason, it is the only form PERQUE uses. Hydroxocobalamin requires no intrinsic factor and is taken up directly by mucous membranes regardless of digestive competence.* Hydroxocobalamin is easily converted to active but shortlived methylcobalamin and adenosyl-cobalamin as needed in the body. Hydroxocobalamin, the parent to other B-12 forms, provides better, long-lived B-12 action in the body. PERQUE ACTIVATED B-12 GUARD FOR SAMe! Optimal absorption of vitamin B-12 is essential to keep SAMe (S-adenosyl methionine) in its beneficial form. SAMe is critical for the manufacture of brain chemicals and for detoxification.* Vegans and vegetarians in particular could be more susceptible as their diets may exclude meat and dairy - the most common sources of vitamin B-12. But the widespread consumption of processed foods is contributing to this problem among all of us. Research shows we're getting 78% less B-12 in our diets now than in the 1960s. Vitamin B-12 in activated hydroxocobalamin form May support healthy energy levels Promotes a healthy nervous system Helps maintain a healthy digestive system Ideal for vegans and vegetarians Dissolvable lozenges *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Suggested Use Adults: As a dietary supplement, take one sublingual lozenge daily or as directed by your healthcare professional. Place lozenge under tongue and let dissolve. Warning: If you are pregnant, nursing, or taking medication, please consult your healthcare professional before using this product. Keep out of the reach of children. Safety-sealed for your protection and for product freshness. Do not use if outer seal is missing or broken. Store in cool, dry place. SUPPLEMENT FACTS Serving size: 1 lozengeServings per container: 100 Ingredients Amount %DV B-12 (hydroxocobalamin) 2,000 mcg 33,330% Mannitol 295 mg † Organic, whole cane juice 1 mg † Raspberry flavor 8.5 mg † 100% Whole cherry fruit extract 2.5 mg † Croscarmellose Sodium 25 mg † Magnesium (as C16 and C18 alkyls from whole, untreated palm fruit and leaf) 3.5 mg † Other Ingredients: no hidden or inactive ingredients † Daily Value not established Contains no: citrus, MSG, wheat, gluten, corn, starch, sugar, wax, soy, yeast, zein, sulfate, phosphates (other than coenzymes), preservatives, casein or other milk derivatives. No GMOs.